Przejdź do treściGeneral Medical Discoveries · Animal study
Researchers produced aggregates of heart muscle cells from human induced pluripotent stem cells and transplanted them into the hearts of monkeys after myocardial infarction. Three months later, substantial, organised human graft tissue was present in the animals’ hearts, and recovery of heart function appeared to vary with the properties of the cardiomyocytes used. Graft-related arrhythmias occurred, although they became less frequent over time. An orthopaedic surgeon following regenerative medicine should distinguish preclinical progress from clinical evidence: this is an important preclinical step toward repairing damaged heart muscle, but it does not yet show that this specific approach is safe or effective in people.
Source: Gruh I, Martens A, et al. Human iPSC-cardiomyocyte-aggregate cell therapy in non-human primates and correlation of heart recovery with contractile and electrophysiological cardiomyocyte properties. Nature Communications. Published 26 August 2026;17:9066. Source publication · PubMed. Prepared from the public abstract and bibliographic record; full text was not used. Source details checked 15 September 2026.
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Content prepared by: Tomasz Poboży - orthopaedic surgeon.